Clinical Study Rivista di neurologia 1990

Hyperbaric oxygen therapy in the treatment of multiple sclerosis. A clinical and electrophysiological study in a 2 year follow-up.

Meneghetti G, Spartà S, Rusca F, Facco E, Martini A, Comacchio F, et al. — Rivista di neurologia, 1990

View Original on PubMed PMID 2247750

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers treated 15 patients with chronic progressive Multiple Sclerosis with hyperbaric oxygen therapy for 20 daily exposures followed by monthly exposures over a 24-month follow-up period.

What They Found

No objective benefit was observed from hyperbaric oxygen therapy in moderating the progression of multiple sclerosis over the 24-month study period. However, a subjective improvement in bladder control was reported by 8 patients in the short-term and by 5 patients in the long-term follow-up. Electrophysiological results showed no significant variations after the initial 20 exposures.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Italy.

Study Limitations

A limitation of this study is its small sample size of 15 patients, which may affect the generalizability of the findings.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	2247750
Year Published	1990
Journal	Rivista di neurologia
MeSH Terms	Adult; Audiometry, Pure-Tone; Chronic Disease; Electronystagmography; Evaluation Studies as Topic; Evoked Potentials, Auditory, Brain Stem; Evoked Potentials, Somatosensory; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Multiple Sclerosis; Time Factors

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology