What Researchers Did
Researchers reviewed animal and human studies on hyperbaric oxygen therapy for cerebral ischaemia and discussed its potential mechanisms of action.
What They Found
Animal studies suggested promise by reducing infarct size and improving neurologic outcomes, and early human reports also indicated benefit. However, recent randomised controlled human studies have not shown benefit, though these studies were limited by small sample sizes.
Canadian Relevance
This review has no specific Canadian connection.
Study Limitations
The human studies reviewed were limited by small sample sizes, contributing to the uncertainty regarding the clinical usefulness of hyperbaric oxygen therapy.