What Researchers Did
Canadian researchers described a patient with myelodysplastic syndrome and aplastic anaemia who received 49 sessions of HBOT alongside allogenic bone marrow transplantation for a complex sacral wound.
What They Found
The sacral wound showed markedly increased granulation tissue in the early HBOT phase. After concurrent bone marrow transplantation, the wound resolved completely and remained healed at one year follow-up. The patient achieved a normocellular bone marrow biopsy.
What This Means for Canadian Patients
Patients with severely compromised blood cell production face major barriers to wound healing. This Canadian case demonstrates that HBOT can promote healing even in the setting of profound bone marrow failure, offering a novel approach for complex wound management.
Canadian Relevance
Canadian study -- case managed at a Canadian institution, with authors from Canadian academic medical centres.
Study Limitations
A single case report cannot establish whether the wound outcome resulted from HBOT, bone marrow transplantation, or their combination.