Case Report J Wound Care 2025 Canadian

Hyperbaric oxygen therapy to promote wound healing in severe pancytopenia: a case report

Brenna C, Khan S, MacDougall M, Tarshis J, Katznelson R, Bahrey L — J Wound Care, 2025

View Original on PubMed PMID 41201880

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Canadian researchers described a patient with myelodysplastic syndrome and aplastic anaemia who received 49 sessions of HBOT alongside allogenic bone marrow transplantation for a complex sacral wound.

What They Found

The sacral wound showed markedly increased granulation tissue in the early HBOT phase. After concurrent bone marrow transplantation, the wound resolved completely and remained healed at one year follow-up. The patient achieved a normocellular bone marrow biopsy.

Canadian Relevance

Canadian study -- case managed at a Canadian institution, with authors from Canadian academic medical centres.

Study Limitations

A single case report cannot establish whether the wound outcome resulted from HBOT, bone marrow transplantation, or their combination.

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Study Details

Study Type	Case Report
Category	Wound Care
Source	Pubmed
PubMed ID	41201880
Year Published	2025
Journal	J Wound Care
MeSH Terms	Humans; Hyperbaric Oxygenation; Wound Healing; Pancytopenia; Male; Bone Marrow Transplantation; Myelodysplastic Syndromes; Anemia, Aplastic

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology