Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial | Canada Hyperbarics Skip to main content
RCT BMC Pediatrics 2009

Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial

Rossignol DA, Rossignol LW, Smith S, et al. — BMC Pediatrics, 2009

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a multicenter, randomized, double-blind, controlled trial to evaluate if hyperbaric oxygen therapy could help children with autism.

What They Found

After 40 sessions, the hyperbaric treatment group showed significant improvements in physician-rated overall functioning, receptive language, social interaction, and eye contact compared to controls. Specifically, 30% of the treatment group was rated "very much improved" or "much improved" by physicians, versus 8% of controls, and 80% showed improvement compared to 38% of controls. Parents also reported significant improvements in overall functioning, receptive language, and eye contact, and the treatment group improved on the Aberrant Behavior Checklist for irritability, stereotypy, hyperactivity, and speech.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

While a controlled trial, this study's findings would benefit from replication in larger, more diverse populations and longer-term follow-up studies.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 19284641
Year Published 2009
Journal BMC Pediatrics

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology