Impact of hyperbaric oxygen therapy on serum lipid profiles and cognitive recovery in patients with post-stroke cognitive impairment: a retrospective cohort study | Canada Hyperbarics Skip to main content
Cohort Study Am J Transl Res 2026

Impact of hyperbaric oxygen therapy on serum lipid profiles and cognitive recovery in patients with post-stroke cognitive impairment: a retrospective cohort study

Hu J, Cheng Y, Qiao Y, Zhou J, Cai M — Am J Transl Res, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This retrospective study compared the effects of hyperbaric oxygen therapy (HBOT) combined with conventional treatment versus conventional treatment alone in 115 patients experiencing cognitive impairment after a stroke.

What They Found

The group receiving HBOT showed significantly greater improvement in cognitive scores, with an average increase of 4.00 points on the MoCA scale compared to 1.63 points in the control group. This group also experienced a greater reduction in LDL-C (bad cholesterol), decreasing by 0.92 mmol/L versus 0.35 mmol/L in the control group. The study found that the reduction in LDL-C mediated 21.07% of the observed cognitive benefit.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a retrospective cohort study, this research may be subject to inherent biases and cannot definitively prove cause-and-effect relationships.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Cohort Study
Category Neurological
Source Pubmed
PubMed ID 42325781
Year Published 2026
Journal Am J Transl Res

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: June 26, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology