Clinical Trial J Nucl Cardiol 2006

Improvement of myocardial perfusion in coronary patients after intermittent hypobaric hypoxia

del Pilar Valle M, García-Godos F, Woolcott O, Marticorena J, Rodríguez V, Gutiérrez I, et al. — J Nucl Cardiol, 2006

View Original on PubMed PMID 16464719

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated if intermittent exposure to low oxygen levels could improve blood flow to the heart in six men with severe coronary artery disease.

What They Found

After 14 sessions of exposure to simulated high altitude (4200 m), participants showed significant improvement in heart blood flow. The summed stress score for reduced blood flow decreased from 9.5 to 4.5, indicating better perfusion (P=.036). No patient experienced worsening heart blood flow after the treatment.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A significant limitation of this study is its very small sample size of only six male patients.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Trial
Category	Cardiac
Source	Pubmed
PubMed ID	16464719
Year Published	2006
Journal	J Nucl Cardiol
MeSH Terms	Chronic Disease; Coronary Artery Disease; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Prognosis; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Treatment Outcome; Ventricular Dysfunction, Left

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology