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Cochrane Review The Cochrane database of systematic reviews 2020 Cochrane

Interventions for frostbite injuries.

Lorentzen AK, Davis C, Penninga L — The Cochrane database of systematic reviews, 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review of randomised controlled trials to assess the benefits and harms of various medical interventions for frostbite injuries.

What They Found

The review aimed to assess interventions such as hyperbaric oxygen therapy, sympathectomy, and thrombolytic therapy for frostbite injuries. However, the abstract does not report specific quantitative findings or conclusive benefits and harms for these interventions, indicating that their effects remain unclear.

Canadian Relevance

This study has no direct Canadian connection, as it is a global systematic review of interventions for frostbite injuries.

Study Limitations

A key limitation is the lack of clear, conclusive evidence regarding the benefits and harms of various interventions for frostbite injuries, as indicated by the review's findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Cochrane Review
Category Neurological
Source Pubmed
PubMed ID 33341943
Year Published 2020
Journal The Cochrane database of systematic reviews
MeSH Terms Amputation, Surgical; Aspirin; Bias; Drug Therapy, Combination; Epoprostenol; Fibrinolytic Agents; Frostbite; Humans; Iloprost; Platelet Aggregation Inhibitors; Pyrrolidines; Recombinant Proteins; Rewarming; Tissue Plasminogen Activator; Vasodilator Agents

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology