Interventions for replacing missing teeth... (2013 study) Skip to main content
Cochrane Review The Cochrane database of systematic reviews 2013 Cochrane

Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants.

Esposito M, Worthington HV, The Cochrane database of systematic reviews, 2013

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed studies on whether hyperbaric oxygen therapy helps dental implants succeed in patients who had radiation treatment for head and neck cancer.

What They Found

This Cochrane systematic review identified only one randomized controlled trial, providing very low quality evidence, comparing hyperbaric oxygen therapy with a control group in irradiated patients getting dental implants. Thirteen patients received hyperbaric oxygen therapy while another group of patients did not. Because only one small trial was found and the evidence quality was very low, the review authors could not determine whether hyperbaric oxygen therapy improves implant success, patient satisfaction, or cost effectiveness compared to not using it.

What This Means for Canadian Patients

For Canadian patients who have had radiation therapy and are considering dental implants, this review shows the evidence on hyperbaric oxygen therapy is currently too limited and too low quality to support firm conclusions either way. Patients in this situation should discuss the very low certainty of this evidence with their care team before deciding on treatment.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The main limitation of this review is that only one small randomized controlled trial was identified, and it provided very low quality evidence, so the findings cannot be considered reliable or generalized.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Cochrane Review
Category Radiation Injury
Source Pubmed
PubMed ID 24085641
Year Published 2013
Journal The Cochrane database of systematic reviews
MeSH Terms Dental Implants; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Mouth, Edentulous; Osteoradionecrosis; Randomized Controlled Trials as Topic

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology