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Systematic Review Diabetes Metab Res Rev 2016 Canadian

Interventions in the management of infection in the foot in diabetes: a systematic review

Peters E, Lipsky B, Aragón-Sánchez J, Boyko E, Diggle M, Embil J, et al. — Diabetes Metab Res Rev, 2016

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

An expert panel systematically reviewed published research on different treatments for foot infections in people with diabetes.

What They Found

This systematic review identified 40 articles, including 37 randomized controlled trials and 3 cohort studies, covering treatments like surgery, topical antiseptics, negative pressure wound therapy, and hyperbaric oxygen. Among these, 15 randomized trials compared new antibiotic regimens for skin and soft tissue infections, generally finding them as effective as conventional treatments, with one study showing them to be more cost-effective.

What This Means for Canadian Patients

For Canadian patients with diabetic foot infections, this review helps inform healthcare providers about the range of available treatments. It suggests that newer antibiotic options are often as effective as conventional ones, potentially offering more choices for managing these serious infections. This comprehensive overview supports evidence-based decisions for improving patient care.

Canadian Relevance

This study has Canadian relevance as one of its authors, J. Embil, is Canadian. It also covers diabetic foot infection, which is a condition related to diabetic foot ulcers, a Health Canada-recognized indication for hyperbaric oxygen therapy.

Study Limitations

The systematic review's findings are limited by the quantity and quality of the studies available for inclusion, with only 40 articles meeting the specific criteria over an extended period.

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Study Details

Study Type Systematic Review
Category Wound Care
Source Pubmed
PubMed ID 26344844
Year Published 2016
Journal Diabetes Metab Res Rev
MeSH Terms Anti-Infective Agents; Anti-Infective Agents, Local; Combined Modality Therapy; Diabetic Foot; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Osteomyelitis; Precision Medicine; Skin Diseases, Infectious; Soft Tissue Infections

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.