Irreversible ischemic hand following intraarterial injection of zolpidem powder. | Canada Hyperbarics Skip to main content
Clinical Study Journal of toxicology. Clinical toxicology 2003

Irreversible ischemic hand following intraarterial injection of zolpidem powder.

Chang MY, Lin JL — Journal of toxicology. Clinical toxicology, 2003

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a case of severe hand ischemia in a 24-year-old woman following intraarterial injection of crushed zolpidem.

What They Found

They found that a 24-year-old woman developed severe right hand ischemia after self-injecting a crushed zolpidem tablet. Despite treatment with heparinization, vasodilators, prostacyclin, and hyperbaric oxygen, the first four digits of her hand remained gangrenous. This was attributed to microvascular embolization from microcrystalline cellulose, a component of zolpidem tablets.

What This Means for Canadian Patients

This case highlights the extreme dangers of injecting oral medications, which can lead to irreversible tissue damage and gangrene. Patients should be aware that crushing and injecting pills can cause severe, permanent harm, even with common medications.

Canadian Relevance

There is no specific Canadian connection mentioned in this study.

Study Limitations

As a single case report, the findings may not be generalizable to all individuals or situations involving intraarterial drug injection.

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Study Details

Study Type Clinical Study
Category Infection
Source Pubmed
PubMed ID 14705853
Year Published 2003
Journal Journal of toxicology. Clinical toxicology
MeSH Terms Adult; Female; Gangrene; Hand; Humans; Hypnotics and Sedatives; Injections, Intra-Arterial; Ischemia; Powders; Pyridines; Substance-Related Disorders; Treatment Failure; Zolpidem

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.