Irreversible ischemic hand following intraarterial injection of zolpidem powder. | Canada Hyperbarics Skip to main content
Clinical Study Journal of toxicology. Clinical toxicology 2003

Irreversible ischemic hand following intraarterial injection of zolpidem powder.

Chang MY, Lin JL — Journal of toxicology. Clinical toxicology, 2003

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a case of severe hand ischaemia in a 24-year-old woman following intraarterial injection of crushed zolpidem.

What They Found

They found that a 24-year-old woman developed severe right hand ischaemia after self-injecting a crushed zolpidem tablet. Despite treatment with heparinization, vasodilators, prostacyclin, and hyperbaric oxygen, the first four digits of her hand remained gangrenous. This was attributed to microvascular embolization from microcrystalline cellulose, a component of zolpidem tablets.

Canadian Relevance

There is no specific Canadian connection mentioned in this study.

Study Limitations

As a single case report, the findings may not be generalizable to all individuals or situations involving intraarterial drug injection.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Infection
Source Pubmed
PubMed ID 14705853
Year Published 2003
Journal Journal of toxicology. Clinical toxicology
MeSH Terms Adult; Female; Gangrene; Hand; Humans; Hypnotics and Sedatives; Injections, Intra-Arterial; Ischemia; Powders; Pyridines; Substance-Related Disorders; Treatment Failure; Zolpidem

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology