What Researchers Did
Researchers documented the case of a 51-year-old man with Rothmund-Thomson syndrome and a persistent leg wound that did not respond to initial treatments, including hyperbaric oxygen therapy, before successful treatment with negative pressure wound therapy and a skin graft.
What They Found
The 51-year-old patient's leg wound did not improve with various local therapies, including hyperbaric oxygen therapy, and gradually enlarged. Complete closure was only achieved after 20 days of negative pressure wound therapy applied at -125 mmHg, followed by a split-thickness skin graft.
What This Means for Canadian Patients
For Canadian patients with Rothmund-Thomson syndrome experiencing unhealing leg ulcers, this case suggests that hyperbaric oxygen therapy may not be effective. Instead, negative pressure wound therapy followed by skin grafting could be a successful treatment option for these difficult wounds.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
As a single case report, the findings of this study cannot be generalized to a larger patient population.