What Researchers Did
Researchers conducted a critical literature review to evaluate existing data on the management of bisphosphonate-related osteonecrosis of the jaw (ONJ).
What They Found
The review found that no treatment protocols for bisphosphonate-related ONJ are currently based on randomized controlled trials. Existing data, including information on teriparatide and hyperbaric oxygen, were critically reviewed to summarize current management strategies.
What This Means for Canadian Patients
Canadian healthcare providers must rely on current literature and clinical judgment to manage bisphosphonate-related ONJ, as definitive, RCT-backed treatment guidelines are unavailable. Patients should discuss all treatment options and potential risks with their care team, understanding that management strategies may vary.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
A key limitation is the absence of randomized controlled trials to establish definitive treatment protocols for bisphosphonate-related osteonecrosis of the jaw.