Case Report Curr Diabetes Rev 2022

Management of Diabetic Foot Ulcers Using Topical Oxygen Therapy: A Case Series

Tabanjeh S, Al-Malki T, Alhazzani A, Robert A — Curr Diabetes Rev, 2022

View Original on PubMed PMID 34636303

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers evaluated topical oxygen therapy (NATROX) in 6 patients with diabetic foot ulcers at a specialized center in Saudi Arabia.

What They Found

Complete wound healing was observed in all 6 patients who received topical oxygen therapy. Healing occurred within a range of 3 to 8 weeks, even in patients with minor amputations or other comorbidities.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Saudi Arabia.

Study Limitations

The study's main limitation is its small sample size of only 6 patients, which limits generalizability and warrants further research.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Report
Category	Wound Care
Source	Pubmed
PubMed ID	34636303
Year Published	2022
Journal	Curr Diabetes Rev
MeSH Terms	Amputation, Surgical; Diabetes Mellitus; Diabetic Foot; Humans; Hyperbaric Oxygenation; Oxygen; Wound Healing

Related Research

Cochrane | 2015 Systematic Review

Hyperbaric oxygen therapy for chronic wounds

Kranke P, Bennett MH, Martyn-St James M, et al.

Ont Health Technol Assess Ser | 2005 Clinical Study ★

Hyperbaric oxygen therapy for non-healing ulcers in diabetes mellitus: an evidence-based analysis

Ontario Medical Advisory Secretariat.

Diabetes Care | 2010 RCT

Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes

Löndahl M, Katzman P, Nilsson A, et al.

Asian J Surg | 2022 Meta-Analysis

Efficacy of hyperbaric oxygen therapy for diabetic foot ulcers: an updated systematic review and meta-analysis

Zhang Z, Yang C, Jiang M, et al.

J Wound Ostomy Continence Nurs | 2017 RCT

Adjunctive hyperbaric oxygen therapy for healing of chronic diabetic foot ulcers: a randomized controlled trial

Chen CY, Wu RW, Hsu MC, et al.

This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology