[Mandibular osteoradionecrosis (ORN) as a side effect of head and neck cancer treatment: Factors that induce it] | Canada Hyperbarics Skip to main content
Study Gac Med Mex 2016

[Mandibular osteoradionecrosis (ORN) as a side effect of head and neck cancer treatment: Factors that induce it]

Gallegos-Hernández J, Reyes-Vivanco A, Arias-Ceballos H, Minauro-Muñoz G, Ortiz-Maldonado A, García-Ruiz D, et al. — Gac Med Mex, 2016

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers looked back at medical records of 250 patients who received radiation therapy for head and neck cancer to identify factors leading to jaw bone damage between 2002 and 2010.

What They Found

Out of 250 patients, 25 (10%) developed osteoradionecrosis of the jaw, with 72% of these cases linked to tooth extraction. Most patients (20 out of 25) needed surgery to remove part of their jaw, and none of the patients in this study received hyperbaric oxygen therapy.

What This Means for Canadian Patients

Canadian patients undergoing radiation for head and neck cancer should prioritize dental check-ups and any necessary dental work before starting treatment to reduce the risk of osteoradionecrosis. Regular monitoring after radiation is also important to catch any signs of jaw bone damage early, potentially preventing the need for extensive surgery.

Canadian Relevance

This study covers osteoradionecrosis, which is a Health Canada-recognized indication for hyperbaric oxygen therapy.

Study Limitations

A limitation is that this retrospective study did not include patients who received hyperbaric oxygen therapy, so it cannot evaluate its potential benefits.

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Study Details

Study Type Study
Category Radiation Injury
Source Pubmed
PubMed ID 27861470
Year Published 2016
Journal Gac Med Mex
MeSH Terms Female; Head and Neck Neoplasms; Humans; Male; Mandible; Mandibular Diseases; Middle Aged; Osteoradionecrosis; Retrospective Studies; Tooth Extraction

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.