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Systematic Review Cancer 2014

MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy

Lalla R, Bowen J, Barasch A, Elting L, Epstein J, Keefe D, et al. — Cancer, 2014

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review of scientific literature to update clinical practice guidelines for managing mucositis, a common side effect of cancer therapy.

What They Found

The literature search identified 8279 papers, with 570 ultimately included for detailed evaluation. This extensive review led to the development of 16 new guidelines, bringing the total number of MASCC/ISOO mucositis guidelines to 32, including 22 for oral mucositis and 10 for gastrointestinal mucositis.

What This Means for Canadian Patients

For Canadian patients undergoing cancer treatment, these updated guidelines provide clinicians with evidence-based strategies to manage mucositis. This can help reduce pain and discomfort, potentially improving patient quality of life and their ability to complete necessary cancer therapies.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The guidelines are based on the scientific literature available at the time of the review, and the quality of the included studies may vary.

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Study Details

Study Type Systematic Review
Category Wound Care
Source Pubmed
PubMed ID 24615748
Year Published 2014
Journal Cancer
MeSH Terms Amifostine; Analgesics; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antineoplastic Agents; Cryotherapy; Cytokines; Esophagitis; Evidence-Based Medicine; Humans; Hyperbaric Oxygenation; Intercellular Signaling Peptides and Proteins; Low-Level Light Therapy; Mucositis; Neoplasms; Oral Hygiene; Phototherapy; Proctitis; Protective Agents; Radiation-Protective Agents; Radiotherapy; Stomatitis; Sucralfate

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.