Metabolically Supported Chemotherapy for Managing... (2021 study) Skip to main content
Case Report Cureus 2021

Metabolically Supported Chemotherapy for Managing End-Stage Breast Cancer: A Complete and Durable Response

İyikesici M, Slocum A, Winters N, Kalamian M, Seyfried T, Cureus, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Doctors reported on a single 47-year-old woman with end-stage breast cancer who was treated with a combination of metabolically supported chemotherapy, a ketogenic diet, hyperthermia, and hyperbaric oxygen therapy.

What They Found

This is a case report describing one patient with T4N3M1 (end-stage, spread to distant sites) breast cancer who received six months of combined metabolically supported chemotherapy, ketogenic diet, hyperthermia, and hyperbaric oxygen therapy, and the abstract states that this protocol eliminated all detectable lesions. The study title describes the outcome as a complete and durable response. As a single case, this result comes from one patient and does not include a comparison group.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a single-patient case report with no control group, this study cannot establish that the treatment caused the outcome or that similar results would occur in other patients.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Case Report
Category Radiation Injury
Source Pubmed
PubMed ID 33927959
Year Published 2021
Journal Cureus

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology