Mild hyperbaric oxygen activates the proliferation of epidermal basal cells in aged mice. | Canada Hyperbarics Skip to main content
Clinical Study The Journal of dermatology 2018

Mild hyperbaric oxygen activates the proliferation of epidermal basal cells in aged mice.

Nishizaka T, Nomura T, Higuchi K, Takemura A, Ishihara A — The Journal of dermatology, 2018

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the impact of mild hyperbaric oxygen exposure on the proliferation of epidermal basal cells in aged mice.

What They Found

They found that mild hyperbaric oxygen exposure, at 1266 hPa with 36% oxygen for 6 hours/day over 1 or 2 weeks, accelerated the proliferative activity of epidermal basal cells in aged mouse skin (34 and 55 weeks old). Epidermal thickness was unaffected across all age groups (5, 34, and 55 weeks).

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or participants.

Study Limitations

A primary limitation is that the study was conducted on aged mice, meaning the findings may not directly translate to humans.

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Study Details

Study Type Clinical Study
Category Uncategorised
Source Pubmed
PubMed ID 29855082
Year Published 2018
Journal The Journal of dermatology
MeSH Terms Animals; Cell Proliferation; Disease Models, Animal; Epidermis; Female; Humans; Hyperbaric Oxygenation; Keratinocytes; Mice; Mice, Hairless; Oxidative Stress; Oxygen; Skin Aging; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.