Clinical Study JAMA 1977

Monoplace hyperbaric oxygen therapy for gas gangrene.

Fowler DL, Evans LL, Mallow JE — JAMA, 1977

View Original on PubMed PMID 196119

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers treated nine patients with gas gangrene using monoplace hyperbaric oxygen therapy, antibiotics, and surgical debridement at St Luke's Hospital of Kansas City.

What They Found

The study observed an 11.1% mortality rate among the nine patients treated for gas gangrene. This suggests that hyperbaric oxygen, combined with antibiotics and surgical debridement, may reduce mortality in such cases.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in the United States.

Study Limitations

A significant limitation of this study is its very small sample size of only nine patients.

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Study Details

Study Type	Clinical Study
Category	Infection
Source	Pubmed
PubMed ID	196119
Year Published	1977
Journal	JAMA
MeSH Terms	Abscess; Aged; Clostridium perfringens; Colostomy; Debridement; Female; Gas Gangrene; Humans; Hyperbaric Oxygenation; Penicillins; Perineum; Rectal Diseases

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology