Retrospective Study RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 2000

MRI evaluation of aseptic osteonecrosis in children over the course of hyperbaric oxygen therapy.

Scherer A, Engelbrecht V, Bernbeck B, May P, Willers R, Göbel U, et al. — RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2000

View Original on PubMed PMID 11111290

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively analyzed MRI scans from 20 children with aseptic osteonecrosis during chemotherapy to evaluate the effect of hyperbaric oxygen therapy.

What They Found

Initially, the hyperbaric oxygen therapy group (Gr. II, n=12) had more severe findings with an average MRI score of 3.4 compared to the control group (Gr. I, n=8) with 2.65. Over time, average scores increased to 3.2 in Gr. I and 4.1 in Gr. II, indicating progression, with no statistically significant difference between the groups.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Germany.

Study Limitations

Limitations include the retrospective design, small sample size, and initial differences in disease severity between the treatment groups.

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Study Details

Study Type	Retrospective Study
Category	Infection
Source	Pubmed
PubMed ID	11111290
Year Published	2000
Journal	RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
MeSH Terms	Antineoplastic Agents; Child; Female; Humans; Hyperbaric Oxygenation; Magnetic Resonance Imaging; Male; Neoplasms; Osteonecrosis; Pain; Retrospective Studies; Weight-Bearing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology