Case Study Hormones (Athens, Greece) 2010

Optic neuropathy following radiotherapy for Cushing's disease: case report and literature review.

Ballian N, Androulakis II, Chatzistefanou K, Samara C, Tsiveriotis K, Kaltsas GA — Hormones (Athens, Greece), 2010

View Original on PubMed PMID 20688625

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report of a patient who developed radiation-induced optic neuropathy following external beam irradiation for a recurrent adrenocorticotrophin secreting pituitary adenoma, alongside a review of the relevant literature.

What They Found

Researchers found that a patient developed radiation-induced optic neuropathy 16 months after receiving external beam irradiation for a recurrent adrenocorticotrophin secreting pituitary adenoma. Despite treatment with glucocorticoids and hyperbaric oxygen, the patient's vision did not improve.

Canadian Relevance

This study has no direct Canadian connection as it is a case report from Greece.

Study Limitations

As a case report, this study's findings are limited by its observational nature and lack of generalizability to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Study
Category	Radiation Injury
Source	Pubmed
PubMed ID	20688625
Year Published	2010
Journal	Hormones (Athens, Greece)
MeSH Terms	ACTH-Secreting Pituitary Adenoma; Adenoma; Combined Modality Therapy; Female; Glucocorticoids; Humans; Hyperbaric Oxygenation; Magnetic Resonance Imaging; Middle Aged; Optic Nerve Diseases; Pituitary ACTH Hypersecretion; Radiation Injuries; Radiotherapy; Treatment Failure; Visual Acuity

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology