Oral implant rehabilitation of patients with oral malignancies treated with radiotherapy and surgery without adjunctive hyperbaric oxygen. | Canada Hyperbarics Skip to main content
Clinical Study The International journal of oral & maxillofacial implants 1995

Oral implant rehabilitation of patients with oral malignancies treated with radiotherapy and surgery without adjunctive hyperbaric oxygen.

Franzén L, Rosenquist JB, Rosenquist KI, Gustafsson I — The International journal of oral & maxillofacial implants, 1995

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers placed 20 dental implants in the irradiated mandibles of five patients who had undergone radiotherapy and surgery for oral malignant tumours, without using adjunctive hyperbaric oxygen therapy.

What They Found

The radiotherapy dose ranged from 25 to 64 Gy (mean 40.3 Gy), with a biologically effective dose between 33.4 and 106.9. Out of 20 implants placed, 19 remained stable after 3 to 6 years of observation, with only one failing to osseointegrate.

What This Means for Canadian Patients

For Canadian patients requiring dental implants after oral cancer treatment involving radiotherapy, this study suggests that adjunctive hyperbaric oxygen therapy might not always be a mandatory step. This could potentially streamline their treatment process and reduce the overall burden of care.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is its very small sample size of only five patients.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 7744437
Year Published 1995
Journal The International journal of oral & maxillofacial implants
MeSH Terms Aged; Combined Modality Therapy; Dental Abutments; Dental Implantation, Endosseous; Dental Implants; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Mandible; Middle Aged; Mouth Neoplasms; Osseointegration; Radiotherapy Dosage

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology