Osteoradionecrosis of the mandible. Treatment with hyperbaric oxygen. | Canada Hyperbarics Skip to main content
Clinical Study Archives of otolaryngology (Chicago, Ill. : 1960) 1975

Osteoradionecrosis of the mandible. Treatment with hyperbaric oxygen.

Mainous EG, Hart GB — Archives of otolaryngology (Chicago, Ill. : 1960), 1975

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effectiveness of hyperbaric oxygen therapy in 14 patients suffering from intractable osteoradionecrosis of the mandible.

What They Found

Among the 14 patients treated with hyperbaric oxygen, favorable responses included relief of pain, elimination of extraoral draining sinus tracts, and the return of osseous union in areas of abnormal fracture. This treatment also led to the rapid dissolution of sequestrum without suppuration, minimizing further tissue loss.

What This Means for Canadian Patients

Canadian patients with intractable osteoradionecrosis of the mandible might benefit from hyperbaric oxygen therapy as a less invasive treatment option. This approach could potentially alleviate pain and promote healing, reducing the need for more aggressive surgical interventions.

Canadian Relevance

This study does not have a direct Canadian connection as it was not conducted in Canada nor involved Canadian participants or institutions.

Study Limitations

A significant limitation of this study is its small sample size of 14 patients and the lack of a control group, which limits the generalizability of the findings.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 804303
Year Published 1975
Journal Archives of otolaryngology (Chicago, Ill. : 1960)
MeSH Terms Adult; Aged; Alveolectomy; Bone Transplantation; Cobalt Radioisotopes; Denture, Complete, Immediate; Female; Follow-Up Studies; Gingival Neoplasms; Glossectomy; Humans; Hyperbaric Oxygenation; Male; Mandibular Diseases; Middle Aged

Cite This Study

Share

Find a Canadian Clinic Treating Radiation Injury

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.