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Review Revista espanola de enfermedades digestivas 2023

"Out of the box" new therapeutic strategies for Crohn´s disease: moving beyond biologics.

Catalán-Serra I, Ricanek P, Grimstad T — Revista espanola de enfermedades digestivas, 2023

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a review discussing promising new "out of the box" therapeutic strategies for Crohn's disease beyond current pharmacological treatments.

What They Found

The review highlighted that almost 50% of Crohn's disease patients do not achieve sustained response with current treatments, necessitating new approaches. Researchers discussed various non-pharmacological strategies including nutritional interventions, cell therapies, microbiota-based treatments, and neuromodulation as potential main or complementary therapies.

What This Means for Canadian Patients

Canadian patients with Crohn's disease who struggle with current treatments may benefit from the exploration of these novel "out of the box" therapies in the future. These strategies aim to improve treatment efficacy, minimize side effects, and enhance quality of life for those living with this chronic condition.

Canadian Relevance

This study does not have a direct Canadian connection.

Study Limitations

As a review, this study synthesizes existing literature, and the discussed "out of the box" therapies require further robust clinical trials to establish their widespread efficacy.

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Study Details

Study Type Review
Category Systematic Reviews
Source Pubmed
PubMed ID 35748460
Year Published 2023
Journal Revista espanola de enfermedades digestivas
MeSH Terms Humans; Biological Products; Crohn Disease; Quality of Life; Inflammation; Enteral Nutrition

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.