Outcomes of Hyperbaric Oxygen Treatment for Central Retinal Artery Occlusion: A Single Center Experience | Canada Hyperbarics Skip to main content
Cohort Study Am J Ophthalmol 2025

Outcomes of Hyperbaric Oxygen Treatment for Central Retinal Artery Occlusion: A Single Center Experience

Kim B, Wang K, Xu T, Hooshmand S, Toups G, Millman M, et al. — Am J Ophthalmol, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed outcomes in 41 patients with central retinal artery occlusion (CRAO) treated with HBOT at the Mayo Clinic over 12 years, examining how treatment timing affected visual acuity recovery.

What They Found

Patients treated within 9 hours of symptom onset had significantly greater visual improvement: 70% showed clinically meaningful improvement versus only 28.6% of those treated after 9 hours (p=0.008). Median improvement was 5.9 lines of vision in the early group versus 0 lines in the delayed group (p<0.001).

What This Means for Canadian Patients

CRAO is essentially a stroke of the eye, and like brain stroke, time is critical. Canadians experiencing sudden vision loss should present to emergency departments immediately, as HBOT may partially restore vision but only if started within approximately 9 hours of symptom onset.

Canadian Relevance

No direct Canadian connection identified. Access to emergency HBOT for CRAO in Canada varies significantly by province and city.

Study Limitations

This is a retrospective single-center study without a control group, making it impossible to determine how much visual recovery was due to HBOT versus natural history.

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Study Details

Study Type Cohort Study
Category Ocular / Retinal
Source Pubmed
PubMed ID 39368618
Year Published 2025
Journal Am J Ophthalmol
MeSH Terms Humans; Hyperbaric Oxygenation; Retinal Artery Occlusion; Retrospective Studies; Male; Female; Visual Acuity; Aged; Treatment Outcome; Middle Aged; Follow-Up Studies; Tomography, Optical Coherence; Fluorescein Angiography; Aged, 80 and over

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.