What Researchers Did
Researchers conducted a scoping review to systematically evaluate the documented adverse events and assess the risks associated with oxygen-ozone autohaemotherapy (O2-O3-AHT) for fibromyalgia.
What They Found
The review identified predominantly case reports detailing rare but potentially serious adverse events linked to O2-O3-AHT. These included haemolysis and renal failure (often with ozone concentrations over 60 μg/mL), hyperkalaemia in patients with existing health conditions, myocardial infarction, cerebral gas embolism, autonomic reactions, anaphylactic reactions, and infectious complications due to protocol breaches. The overall incidence of serious adverse events could not be reliably quantified due to a lack of prospective registries and reliable data.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
The overall incidence of serious adverse events cannot be reliably quantified given the absence of prospective registries and reliable denominator data.