What Researchers Did
Researchers conducted a literature review using MEDLINE/PubMed to examine hemorrhagic cystitis in paediatric bone-marrow transplant patients.
What They Found
The incidence of hemorrhagic cystitis in paediatric bone-marrow transplant patients is estimated to be 10-20%. Evidence suggests a link between BK virus and hemorrhagic cystitis, though other contributing factors are likely. Current preventive and therapeutic strategies show modest advances but require further validation.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The review highlights the lack of evidence-based treatment guidelines and the need for prospective randomised studies to validate current preventive and therapeutic strategies.