What Researchers Did
Researchers retrospectively analyzed 81 cases of perineal gangrene treated at a single center with a combined medico-surgical protocol, including intensive care, extensive excisions, drainage, and hyperbaric oxygen therapy.
What They Found
The study found a mortality rate of 24.7% among the 81 patients, with a mean intensive care stay of 19 days and a mean hospital stay of 31 days. Significant risk factors included age over 68 years (p = 0.001) and a severity index greater than 10 (p = 0.003), while 3 patients experienced anal incontinence and 5 required a permanent colostomy.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
As a retrospective study conducted at a single center, the generalizability of these findings may be limited.