What Researchers Did
Researchers conducted a single-center retrospective case series at the University Hospital of Copenhagen, reviewing 11 adult patients with culture-confirmed periorbital Group A streptococcus infections over a 14-month period.
What They Found
The study included 11 patients with periorbital GAS infections, with a median age of 72 years; four patients had diabetes and two developed septic shock. Six cases were diagnosed with pre-septal cellulitis, while five had post-septal necrotizing soft tissue infection (NSTI) confirmed by surgery, with these NSTI cases showing the MLST 28 / emm 1.0 (M1 clone) GAS type.
Canadian Relevance
This study has no direct Canadian connection as it was conducted at a single center in Copenhagen, Denmark.
Study Limitations
The study's retrospective, single-center design and small sample size limit the generalizability of its findings.