Platet Rich Plasma or Hyperbaric Oxygen Therapy as callus accellerator in aseptic tibial non union. Evaluate of outcomes | Canada Hyperbarics Skip to main content
Study Acta Biomed 2020

Platet Rich Plasma or Hyperbaric Oxygen Therapy as callus accellerator in aseptic tibial non union. Evaluate of outcomes

Rollo G, Bonura E, Falzarano G, Bisaccia M, Ribes Iborra J, Grubor P, et al. — Acta Biomed, 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared two groups of 50 patients with aseptic tibial non-union, one treated with the Ilizarov technique plus Platelet Rich Plasma (PRP) and the other with the Ilizarov technique plus Hyperbaric Oxygen Therapy (HBOT), to evaluate which method offered advantages.

What They Found

The study found that patients treated with HBOT experienced significantly more local skin inflammation and skin retraction compared to the PRP group (p<0.05). Conversely, the PRP group had significantly more refractures than the HBOT group (p<0.05).

What This Means for Canadian Patients

For Canadian patients with aseptic tibial non-union, this study suggests that HBOT as an add-on to Ilizarov treatment might reduce the risk of refracture compared to PRP, but could increase local skin complications. Patients should discuss these potential benefits and risks with their healthcare providers when considering treatment options for complex bone healing.

Canadian Relevance

No direct Canadian connection identified. Tibial non-union is not a Health Canada-recognized indication for HBOT.

Study Limitations

This study was limited by its retrospective design for one patient group and a relatively small sample size of 50 patients.

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Study Details

Study Type Study
Category Wound Care
Source Pubmed
PubMed ID 33525281
Year Published 2020
Journal Acta Biomed
MeSH Terms Fracture Healing; Humans; Hyperbaric Oxygenation; Platelet-Rich Plasma; Quality of Life; Reproducibility of Results; Retrospective Studies; Tibial Fractures

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.