Clinical Study Zhonghua er bi yan hou ke za zhi 2002

Preliminary clinical study of application of cyntridini triphosphatis and dexamethasone in treatment of sudden deafness.

Luo W, Liu S, Liang C, Liu Y, Zhou C, Cao Q, et al. — Zhonghua er bi yan hou ke za zhi, 2002

View Original on PubMed PMID 12772414

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomised clinical study involving 207 patients with sudden deafness to investigate the effect of cytridini triphosphatis (CTP) combined with dexamethasone.

What They Found

After treatment, the average hearing threshold decreased by 50.08 dB HL in the CTP group compared to 19.45 dB in the control group (P < 0.05). This indicates that CTP combined with dexamethasone significantly improved treatment effects and enhanced the recovery rate for sudden deafness patients.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada and does not involve Canadian researchers or participants.

Study Limitations

A key limitation is that the exact mechanism by which cytridini triphosphatis combined with dexamethasone improves sudden deafness remains unknown.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type	Clinical Study
Category	Uncategorised
Source	Pubmed
PubMed ID	12772414
Year Published	2002
Journal	Zhonghua er bi yan hou ke za zhi
MeSH Terms	Adolescent; Adult; Aged; Audiometry, Pure-Tone; Cytidine Triphosphate; Dexamethasone; Drug Therapy, Combination; Female; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Male; Middle Aged

Related Research

J Int Med Res | 2004 RCT

Effectiveness of hyperbaric oxygen therapy in the treatment of complex regional pain syndrome

Kiralp MZ, Yildiz S, Vural D, et al.

Undersea Hyperb Med | 2013 Clinical Study

The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome

Akarsu S, Tekin L, Ay H, et al.

Int J Med Sci | 2024 Retrospective Study

The effectiveness of hyperbaric oxygen treatment in patients with complex regional pain syndrome: a retrospective case series

Hajek M, Hadanny A, Engel-Yeger B, et al.

BMJ Open | 2024 RCT

Protocol for a multicentric, double-blind, randomised controlled trial of HBOT versus sham for vaso-occlusive crisis in sickle cell disease (HBOT-SCD study)

Stirnemann J, Serratrice J, Mann T, et al.

Undersea Hyperb Med | 2024 RCT

Outcomes after pancreaticoduodenectomy with or without preoperative hyperbaric oxygen therapy

Jacoby H, Camporesi EM, Ross SB, et al.

See all Uncategorised research

View on PubMed Back to Research Library

Find a Canadian Clinic Treating Uncategorised

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology