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Clinical Trial J Cancer Res Clin Oncol 1996

Radiotherapy after hyperbaric oxygenation for malignant gliomas: a pilot study

Kohshi K, Kinoshita Y, Terashima H, Konda N, Yokota A, Soejima T — J Cancer Res Clin Oncol, 1996

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared the outcomes of radiotherapy combined with hyperbaric oxygen therapy against radiotherapy alone in patients with malignant brain tumours.

What They Found

In patients receiving hyperbaric oxygen therapy alongside radiotherapy, all 9 patients (100%) experienced more than 50% tumor regression, with complete disappearance in 4 patients (44%). In contrast, only 4 out of 12 patients (33%) receiving radiotherapy alone showed any decrease in tumor size, and all 12 patients in this group died within 36 months.

What This Means for Canadian Patients

This pilot study suggests that hyperbaric oxygen therapy could potentially enhance the effectiveness of radiotherapy for Canadian patients battling malignant gliomas, a severe form of brain cancer. The findings indicate a promising avenue for improving tumour response, offering a potential new strategy to consider in treatment plans.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a pilot study, this research involved a small number of participants and requires further investigation with larger, controlled trials to confirm these promising initial findings.

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Study Details

Study Type Clinical Trial
Category Radiation Injury
Source Pubmed
PubMed ID 8898978
Year Published 1996
Journal J Cancer Res Clin Oncol
MeSH Terms Adolescent; Aged; Astrocytoma; Female; Glioblastoma; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Pilot Projects; Radiation-Sensitizing Agents

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.