Clinical Study Journal of infection and public health 2023

Real-world evidence of hyperbaric oxygen therapy on cardiovascular outcomes in patients with chronic osteomyelitis.

Tai CJ, Lu CK, Lee CY, Lee SS, Yang YH — Journal of infection and public health, 2023

View Original on PubMed PMID 36940497

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a population-based cohort study using the Taiwan National Health Insurance Database to evaluate the impact of hyperbaric oxygen (HBO) therapy on cardiovascular outcomes and mortality in 5312 patients with chronic osteomyelitis.

What They Found

After propensity-score matching, the hyperbaric oxygen (HBO) group showed significantly lower 1-year mortality (HR 0.49; 95% CI, 0.25-0.95) compared to the non-HBO group. The HBO group also experienced a lower risk of stroke (HR 0.46; 95% CI, 0.34-0.63), but HBO therapy did not reduce the risk of myocardial infarction.

Canadian Relevance

This study was conducted using data from Taiwan and does not have a direct Canadian connection.

Study Limitations

As an observational cohort study, it cannot establish causality and may be subject to unmeasured confounding factors.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	36940497
Year Published	2023
Journal	Journal of infection and public health
MeSH Terms	Humans; Hyperbaric Oxygenation; Cohort Studies; Osteomyelitis; Stroke; Myocardial Infarction

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology