Relationship between ulcer healing after hyperbaric oxygen therapy and transcutaneous oximetry, toe blood pressure and ankle-brachial index in patients with diabetes and chronic foot ulcers | Canada Hyperbarics Skip to main content
RCT Diabetologia 2011

Relationship between ulcer healing after hyperbaric oxygen therapy and transcutaneous oximetry, toe blood pressure and ankle-brachial index in patients with diabetes and chronic foot ulcers

Löndahl M, Katzman P, Hammarlund C, Nilsson A, Landin-Olsson M — Diabetologia, 2011

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers evaluated whether baseline circulatory variables could predict ulcer healing after hyperbaric oxygen therapy (HBOT) in diabetic patients with chronic foot ulcers.

What They Found

In the HBOT group, transcutaneous oximetry (TcPO₂) levels were significantly lower for patients whose ulcers did not heal compared to those whose ulcers healed. A significantly increased healing frequency was observed with increasing TcPO₂ levels, ranging from 0% healing for 75 mmHg. No statistically significant relationship was found between toe blood pressure or ankle-brachial index and healing frequency.

What This Means for Canadian Patients

For Canadian patients with diabetes and chronic foot ulcers, measuring transcutaneous oximetry (TcPO₂) could help identify those most likely to benefit from hyperbaric oxygen therapy. This could lead to more targeted and effective treatment plans, potentially improving healing rates and optimizing resource allocation.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Sweden.

Study Limitations

The study was a secondary analysis of a subset of participants from a larger trial, which may limit the generalizability of the findings.

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Study Details

Study Type RCT
Category Wound Care
Source Pubmed
PubMed ID 20957342
Year Published 2011
Journal Diabetologia
MeSH Terms Ankle Brachial Index; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Diabetic Foot; Humans; Hyperbaric Oxygenation

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.