Clinical Study Spinal cord series and cases 2021

Reshaping cortical connectivity in traumatic spinal cord injury: a novel effect of hyperbaric oxygen therapy.

Marrosu F, Mancosu S, Lai G, Fraschini M, Muroni A, Demuru M, et al. — Spinal cord series and cases, 2021

View Original on PubMed PMID 34504060

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effect of hyperbaric oxygen therapy (HBO2) on cortical connectivity in a 45-year-old male patient with severe traumatic spinal cord injury (SCI).

What They Found

The patient experienced dramatic clinical improvement and optimization of single performances after HBO2 cycles. EEG recordings revealed a substantial reshaping of cortico-cortical connectivity in sensory-motor areas, correlating with the positive clinical evolution.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada.

Study Limitations

A significant limitation of this study is that it is a single case report, limiting the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	34504060
Year Published	2021
Journal	Spinal cord series and cases
MeSH Terms	Humans; Hyperbaric Oxygenation; Male; Spinal Cord Injuries

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology