What Researchers Did
Researchers conducted a systematic review of non-hyperbaric oxygen interventions for mild traumatic brain injury published between 2005 and 2015 in military and civilian populations.
What They Found
They reviewed 154 abstracts, including seven randomized controlled trials and five pilot studies. Findings indicated that most studies were small pilot interventions focusing on rehabilitation therapy or virtual reality gaming, highlighting a lack of large-scale, well-controlled trials, though some exploratory studies showed promising results.
What This Means for Canadian Patients
For Canadian patients with mild traumatic brain injury, this review underscores the ongoing need for effective treatments, as no standard-of-care currently exists. While large-scale evidence is lacking, small exploratory studies suggest potential new interventions may emerge.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
A primary limitation was the scarcity of large-scale, well-controlled trials on non-hyperbaric oxygen interventions for mild traumatic brain injury within the review period.