Systematic Review Front Neurol 2024

Systematic review and dosage analysis: hyperbaric oxygen therapy efficacy in the treatment of posttraumatic stress disorder

Zilberman-Itskovich S, Catalogna M, Sasson E, et al. — Front Neurol, 2024

View Original on PubMed PMID 38882688

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review and dosage analysis of hyperbaric oxygen therapy (HBOT) for posttraumatic stress disorder (PTSD) symptoms, searching PubMed, CINAHL, and Cochrane databases for adult clinical studies.

What They Found

Eight studies, totaling 393 subjects, were included, comprising seven randomised trials and one imaging case-controlled study. Patients treated with 40-60 HBOT sessions showed statistically significant symptomatic improvements and clinically significant changes in PTSD symptoms.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation of this review is that all included studies had small sample sizes, with fewer than 75 subjects per study.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Systematic Review
Category	Neurological
Source	Pubmed
PubMed ID	38882688
Year Published	2024
Journal	Front Neurol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology