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Systematic Review J Plast Reconstr Aesthet Surg 2017

Systematic review of hyperbaric oxygen therapy for the treatment of radiation-induced skin necrosis

Borab Z, Mirmanesh M, Gantz M, Cusano A, Pu L — J Plast Reconstr Aesthet Surg, 2017

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review following PRISMA guidelines to evaluate the effectiveness of hyperbaric oxygen therapy for radiation-induced skin necrosis.

What They Found

They identified eight articles, comprising one observational cohort, five case series, and two case reports. These articles described symptom changes and altered wound healing of radiation-induced skin necrosis after hyperbaric oxygen therapy, showing promising outcomes.

What This Means for Canadian Patients

Canadian patients experiencing radiation-induced skin necrosis may find hyperbaric oxygen therapy to be a safe intervention with promising outcomes. However, more extensive research is required to establish it as a standard treatment option.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The review was limited by the small number of identified studies, which primarily consisted of lower-level evidence such as case series and case reports.

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Study Details

Study Type Systematic Review
Category Wound Care
Source Pubmed
PubMed ID 28081957
Year Published 2017
Journal J Plast Reconstr Aesthet Surg
MeSH Terms Anti-Bacterial Agents; Debridement; Humans; Hyperbaric Oxygenation; Necrosis; Radiation Injuries; Radiotherapy; Skin; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.