Systematic Review of Traumatic Brain Injury and the Impact of Antioxidant Therapy on Clinical Outcomes | Canada Hyperbarics
Systematic Review Worldviews Evid Based Nurs 2016

Systematic Review of Traumatic Brain Injury and the Impact of Antioxidant Therapy on Clinical Outcomes

Shen Q, Hiebert J, Hartwell J, Thimmesch A, Pierce J — Worldviews Evid Based Nurs, 2016

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review of studies published between 2005 and 2015 to examine the use of antioxidant therapies in treating traumatic brain injury (TBI).

What They Found

After reviewing six studies, the researchers found that antioxidant therapies like amino acids, vitamins C and E, progesterone, N-acetylcysteine, and enzogenol appear to be safe and effective additional treatments for adults with TBI. The overall trend across these studies indicated a positive impact of antioxidant therapies on improving clinical outcomes for TBI patients.

What This Means for Canadian Patients

For Canadian patients with traumatic brain injury, this review suggests that adding antioxidant therapies to their current treatment plan could potentially help reduce brain damage caused by oxidative stress. These findings might encourage healthcare providers to consider these adjunctive treatments to optimize recovery for TBI patients.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The review was limited by the small number of studies (six) that met the inclusion criteria, and the abstract did not specify the nature of other limitations found.

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Study Details

Study Type Systematic Review
Category Neurological
Source Pubmed
PubMed ID 27243770
Year Published 2016
Journal Worldviews Evid Based Nurs
MeSH Terms Acetylcysteine; Adult; Amino Acids; Antioxidants; Ascorbic Acid; Brain Injuries, Traumatic; Female; Flavonoids; Humans; Male; Progesterone; Quercetin; Treatment Outcome; Vitamin E

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.