The effect of hyperbaric oxygen therapy on central... (2025 study) Skip to main content
Study Cutan Ocul Toxicol 2025

The effect of hyperbaric oxygen therapy on central corneal thickness and anterior segment parameters

Cömerter D, Aslan Y, Kalalı Issı E, Sarıdoğan M, Baysal T, Uslu Doğan C, Cutan Ocul Toxicol, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers measured eye and cornea changes in 92 patients before and right after they received hyperbaric oxygen therapy for other medical conditions.

What They Found

This observational study of 92 patients found statistically significant changes in three corneal and eye measurements after hyperbaric oxygen therapy. Central corneal thickness decreased slightly, from 529.69 to 526.63 micrometers (p equals 0.002), and corneal volume decreased from 58.63 to 58.21 cubic millimeters (p equals 0.016). Anterior chamber volume increased from 124.38 to 126.42 cubic millimeters (p equals 0.003). When comparing diabetic patients (22) to non-diabetic patients (70), the abstract reports no substantial difference in how much CCT and corneal volume changed between the two groups, though diabetic patients had significantly lower anterior chamber volume before treatment began (p equals 0.01 and p equals 0.042).

What This Means for Canadian Patients

This study does not address whether hyperbaric oxygen therapy helps or is used for any eye condition. It only reports that corneal and anterior chamber measurements shifted slightly during a course of HBOT given for other, non-eye conditions. The abstract does not state whether these measured changes affect vision, comfort, or eye health.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study measured changes only immediately before and after treatment in a single group without a control arm, so it cannot show whether these corneal changes are temporary, lasting, or caused by HBOT itself rather than other factors.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Study
Category Wound Care
Source Pubmed
PubMed ID 40272842
Year Published 2025
Journal Cutan Ocul Toxicol
MeSH Terms Humans; Hyperbaric Oxygenation; Male; Female; Cornea; Middle Aged; Adult; Aged; Corneal Topography; Anterior Eye Segment

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology