The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial | Canada Hyperbarics Skip to main content
RCT Sci Rep 2023

The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial

Leitman M, Efrati S, Fuchs S, et al. — Sci Rep, 2023

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized, sham-controlled, double-blind trial with 60 post-COVID-19 patients to evaluate the effect of 40 daily hyperbaric oxygen therapy sessions on cardiac function.

What They Found

At baseline, 29 (48.3%) patients had reduced global longitudinal strain (GLS). Following hyperbaric oxygen therapy, GLS significantly increased from -17.8 ± 1.1 to -20.2 ± 1.0 (p = 0.0001) in the HBOT group compared to the sham group, indicating improved left ventricular systolic function. This improvement showed a significant group-by-time interaction (p = 0.041).

What This Means for Canadian Patients

For Canadian patients experiencing persistent post-COVID-19 symptoms and subclinical cardiac dysfunction, hyperbaric oxygen therapy may offer a new therapeutic option to improve heart function. This could potentially alleviate some long-term cardiovascular complications associated with post-COVID-19 syndrome.

Canadian Relevance

This study has no direct Canadian connection. However, the findings are relevant globally as post-COVID-19 syndrome affects patients worldwide, including in Canada.

Study Limitations

The study's limitations include the need for further research to optimize patient selection and evaluate the long-term outcomes of hyperbaric oxygen therapy.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 37301934
Year Published 2023
Journal Sci Rep

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.