The effect of hyperbaric oxygen therapy on treatment of late healed wounds after pharyngeal and laryngeal surgery | Canada Hyperbarics Skip to main content
RCT Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2011

The effect of hyperbaric oxygen therapy on treatment of late healed wounds after pharyngeal and laryngeal surgery

Jiang W, Liang D, Zhang H, Shang W, Wang P, Li W — Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2011

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomised controlled trial involving 83 patients to investigate the effect of hyperbaric oxygen therapy on late-healed wounds after pharyngeal and laryngeal cancer surgery.

What They Found

Patients receiving hyperbaric oxygen (HBO) therapy showed significantly faster wound healing compared to controls. For instance, average healing time for necrosectomy wounds was 27.50 days with HBO versus 45.00 days for controls (P < 0.01). Similarly, pharyngeal fistulas healed in 8.50 days with HBO compared to 14.09 days in controls (P < 0.01), and infected wounds healed in 5.93 days versus 8.62 days (P < 0.01).

What This Means for Canadian Patients

Hyperbaric oxygen therapy could potentially accelerate the healing of complex surgical wounds following head and neck cancer surgery. This might lead to reduced hospital stays and improved recovery for Canadian patients experiencing delayed wound healing.

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

The study was conducted in a single center and involved a relatively small number of patients, which may limit the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Wound Care
Source Pubmed
PubMed ID 21469386
Year Published 2011
Journal Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
MeSH Terms Adult; Aged; Female; Humans; Hyperbaric Oxygenation; Laryngeal Neoplasms; Male; Middle Aged; Otorhinolaryngologic Surgical Procedures; Postoperative Period; Treatment Outcome; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology