Prospective Study Respiratory care 2020

The Impact of High-Flow Nasal Cannula on Olfactory Function.

Adiyeke E, Saatci O, Coskun N, Uludag Kiziltepe HF, Dogru OU, Bakan N — Respiratory care, 2020

View Original on PubMed PMID 32071128

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a prospective observational study comparing olfactory function in 30 acute respiratory failure patients before and after high-flow nasal cannula (HFNC) oxygen therapy, and against 30 healthy controls.

What They Found

Healthy controls had significantly higher baseline olfactory scores (OT, OD, OI, TDI) compared to acute respiratory failure (ARF) patients (p<0.001 for all). Furthermore, HFNC therapy significantly improved olfactory function in ARF patients (p<0.001 for all).

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or with Canadian participants.

Study Limitations

A limitation of this study is its relatively small sample size and single-center, observational design.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Prospective Study
Category	Uncategorised
Source	Pubmed
PubMed ID	32071128
Year Published	2020
Journal	Respiratory care
MeSH Terms	Cannula; Humans; Oxygen; Oxygen Inhalation Therapy; Prospective Studies; Smell

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology