Clinical Study Aviation, space, and environmental medicine 1997

The influence of hyperbaric oxygenation on leukocyte viability and surface protein expression.

McIntyre KM, Dixon PS, Krock LP, Piepmeier EH — Aviation, space, and environmental medicine, 1997

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers studied the effects of hyperbaric oxygenation, oxygen, or carbon dioxide exposure on promyelocytic leukemic HL60 cells for 72 hours.

What They Found

They found that the proliferation rate and viability of HL60 cells were significantly lower (p < 0.05) in the hyperbaric oxygenation groups compared to controls. Hyperbaric treatment led to decreased expression of CD13 and CD38, increased expression of CD11b, CD14, and CD16, while CD10, CD15, and HLADR remained unchanged.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation of this study is that it was conducted on a single cell line in vitro, which may not fully reflect the complex biological environment in living organisms.

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Study Details

Study Type	Clinical Study
Category	Uncategorised
Source	Pubmed
PubMed ID	9408564
Year Published	1997
Journal	Aviation, space, and environmental medicine
MeSH Terms	Antigens, CD; Cell Count; Cell Differentiation; Cell Division; Cell Survival; HL-60 Cells; Humans; Hyperbaric Oxygenation; Leukocytes; Membrane Proteins; Oxygen

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.