Meta-Analysis Nigerian journal of clinical practice 2018

The neuroprotection effect of oxygen therapy: A systematic review and meta-analysis.

Deng Z, Chen W, Jin J, Zhao J, Xu H — Nigerian journal of clinical practice, 2018

View Original on PubMed PMID 29607850

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis to evaluate the efficacy of normobaric oxygen (NBO) and hyperbaric oxygen (HBO) therapies in patients with stroke and traumatic brain injury (TBI).

What They Found

In stroke patients, normobaric oxygen (NBO) significantly improved reperfusion rates, while hyperbaric oxygen (HBO) showed no favorable outcome. For traumatic brain injury (TBI) patients, HBO significantly improved Glasgow outcome scale scores and reduced overall mortality, and NBO appeared to improve brain metabolism.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's limitations likely include potential heterogeneity among the included studies and the quality of the original research.

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Study Details

Study Type	Meta-Analysis
Category	Neurological
Source	Pubmed
PubMed ID	29607850
Year Published	2018
Journal	Nigerian journal of clinical practice
MeSH Terms	Animals; Brain Injuries, Traumatic; Humans; Hyperbaric Oxygenation; Male; Neuroprotection; Neuroprotective Agents; Oxygen; Oxygen Inhalation Therapy; Stroke; Treatment Outcome

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology