What Researchers Did
Researchers conducted a literature review of clinical and basic science studies to summarize the role of oxygen in wound healing.
What They Found
The review found that both the absence (hypoxia) and presence of oxygen influence wound healing, with hypoxia potentially initiating healing via specific factors. While oxygen is often needed for other healing processes, evidence for the efficacy of hyperbaric and topical oxygen therapies is inconsistent, and robust case-controlled prospective studies are lacking.
Canadian Relevance
This study has no specific Canadian connection.
Study Limitations
A key limitation is that the role of oxygen in wound healing is not completely understood, and robust case-controlled prospective studies are lacking for specific oxygen therapies.