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Review Wound Repair Regen 2008

The use of hyperbaric oxygen therapy to treat chronic wounds: A review

Thackham J, McElwain D, Long R — Wound Repair Regen, 2008

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a review of existing literature on hyperbaric oxygen therapy (HBOT) as an adjunctive treatment for chronic, non-healing wounds.

What They Found

They found that hyperbaric oxygen therapy (HBOT) aids in the healing of ulcerated wounds and reduces the risk of amputation in diabetic patients. However, the precise biological mechanisms by which HBOT promotes wound repair, such as up-regulation of angiogenesis and collagen synthesis, are not fully understood, leading to empirical treatment protocols.

Canadian Relevance

This review does not have a direct Canadian connection.

Study Limitations

A key limitation is the lack of clarity regarding the precise biological mechanisms by which hyperbaric oxygen therapy promotes wound healing, leading to empirical treatment protocols.

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Study Details

Study Type Review
Category Wound Care
Source Pubmed
PubMed ID 18471250
Year Published 2008
Journal Wound Repair Regen
MeSH Terms Animals; Chronic Disease; Clinical Protocols; Fibroblasts; Homeostasis; Humans; Hyperbaric Oxygenation; Models, Theoretical; Oxygen; Treatment Outcome; Wound Healing; Wounds and Injuries

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology