Transcutaneous Oximetry Optimizes Clinical Management and Cost-Effectiveness of Diabetic Foot Ulcers Treated with Hyperbaric Oxygen: A Review of Point-of-Care Vascular Screening Options | Canada Hyperbarics Skip to main content
Review Undersea Hyperb Med 2025

Transcutaneous Oximetry Optimizes Clinical Management and Cost-Effectiveness of Diabetic Foot Ulcers Treated with Hyperbaric Oxygen: A Review of Point-of-Care Vascular Screening Options

Clarke R — Undersea Hyperb Med, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

A hyperbaric medicine specialist reviewed the evidence on how transcutaneous oximetry (TcPO2), a skin oxygen measurement test, should be used to select which diabetic foot ulcer patients will benefit from HBOT and when to stop treatment.

What They Found

Transcutaneous oximetry is the only point-of-care test that directly measures tissue oxygen tension at the wound site. TcPO2 testing can identify patients whose wound hypoxia reverses with HBOT (responders) versus those it does not (non-responders), typically detectable within the first few treatment sessions. Newer technologies like near-infrared spectroscopy and thermal imaging provide additional information but do not replace TcPO2 for guiding HBOT dosing decisions.

What This Means for Canadian Patients

For Canadians receiving HBOT for diabetic foot ulcers, an OHIP-covered indication in Ontario, this review argues that TcPO2 testing should be used to confirm a patient is actually responding to HBOT before continuing a full 40-session course. This could prevent unnecessary treatments and focus resources on patients who will genuinely benefit.

Canadian Relevance

Diabetic foot ulcers are an OHIP-covered HBOT indication in Ontario.

Study Limitations

This is a narrative expert review, not a controlled study, so the recommendations reflect one expert's synthesis rather than a formal evidence appraisal.

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Study Details

Study Type Review
Category Wound Care
Source Pubmed
PubMed ID 41429030
Year Published 2025
Journal Undersea Hyperb Med
MeSH Terms Humans; Hyperbaric Oxygenation; Diabetic Foot; Cost-Benefit Analysis; Blood Gas Monitoring, Transcutaneous; Oxygen Saturation; Spectroscopy, Near-Infrared; Thermography; Point-of-Care Systems; Patient Selection; Oximetry; Hypoxia

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.