Treatment of ulcerative compared to non-ulcerative interstitial cystitis with hyperbaric oxygen: a pilot study | Canada Hyperbarics Skip to main content
Pilot Study Ther Adv Urol 2017

Treatment of ulcerative compared to non-ulcerative interstitial cystitis with hyperbaric oxygen: a pilot study

Wenzler D, Gulli F, Cooney M, Chancellor M, Gilleran J, Peters K — Ther Adv Urol, 2017

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers studied how hyperbaric oxygen therapy, given as 30 treatments over 6 weeks, affected patients with ulcerative and non-ulcerative interstitial cystitis.

What They Found

Of the six patients with ulcerative interstitial cystitis (UIC), 83% reported improvement on a global response assessment, with 66% remaining better at 6 months. Pain scores for UIC patients improved by 2 points, and ulcers resolved in two patients by 6-month cystoscopy. In contrast, only one of the two non-ulcerative interstitial cystitis (NIC) patients improved, and their pain scores worsened by 1.5 points, though questionnaire scores improved in both groups.

What This Means for Canadian Patients

For Canadian patients suffering from interstitial cystitis, particularly those with the ulcerative form, this pilot study suggests that hyperbaric oxygen therapy might offer a new treatment option for symptom relief. While the findings are preliminary, they indicate potential for reducing pain and improving overall well-being for some patients, especially those with Hunner's ulcers.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a pilot study with a very small number of participants, limiting the generalizability and statistical power of the findings.

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Study Details

Study Type Pilot Study
Category Wound Care
Source Pubmed
PubMed ID 29383031
Year Published 2017
Journal Ther Adv Urol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.