Use of hyperbaric oxygen therapy (HBOT) in chronic diabetic wound - A randomised trial | Canada Hyperbarics Skip to main content
RCT Med J Malaysia 2019

Use of hyperbaric oxygen therapy (HBOT) in chronic diabetic wound - A randomised trial

Nik Hisamuddin N, Wan Mohd Zahiruddin W, Mohd Yazid B, Rahmah S — Med J Malaysia, 2019

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers ran a randomized controlled trial in 58 patients with Wagner Grade 2 or higher diabetic foot ulcers at two Malaysian tertiary hospitals, comparing conventional wound care alone versus wound care plus HBOT at 2.4 ATA for 90 minutes over 30 days.

What They Found

Wound size decreased significantly faster in the HBOT group at day 10, 20, and 30 (p < 0.001). HBOT patients were 44 times more likely to achieve at least 30% wound reduction within the study period (95% CI: 7.18 to 268.97).

What This Means for Canadian Patients

This RCT directly supports HBOT for diabetic foot ulcers -- an OHIP-covered indication in Ontario. Canadian patients with Wagner Grade 2 or higher wounds not healing with standard care have strong evidence supporting the addition of HBOT to their treatment plan.

Canadian Relevance

Diabetic foot ulcers are an OHIP-covered indication for HBOT in Ontario.

Study Limitations

The study had only a 30-day follow-up; longer-term outcomes including amputation prevention and complete healing were not reported.

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Study Details

Study Type RCT
Category Wound Care
Source Pubmed
PubMed ID 31649219
Year Published 2019
Journal Med J Malaysia
MeSH Terms Chronic Disease; Diabetic Foot; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.