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Pilot Study Crit Care Nurs Q 2013

Use of hyperbaric oxygenation in neonatal patients: a pilot study of 8 patients

Sánchez E — Crit Care Nurs Q, 2013

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a pilot study to see if hyperbaric oxygen therapy could help treat eight newborn babies with brain injury from lack of oxygen (hypoxic-ischaemic encephalopathy) or severe gut inflammation (necrotizing enterocolitis).

What They Found

All eight ventilator-dependent neonates showed resolution of their conditions after receiving hyperbaric oxygen therapy at 2.0 ATA for 45 minutes. Significant improvements (P < .05) were observed in blood markers like haemoglobin, hematocrit, total proteins, serum sodium, triglycerides, and pH, with no adverse effects reported. The study also noted a marked reduction in illness and death among the treated infants.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a small pilot study without a control group, meaning its findings need to be confirmed by larger, more rigorous research.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Pilot Study
Category Infection
Source Pubmed
PubMed ID 23736667
Year Published 2013
Journal Crit Care Nurs Q
MeSH Terms Critical Illness; Electroencephalography; Enterocolitis, Necrotizing; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Hypoxia-Ischemia, Brain; Infant, Newborn; Intensive Care Units, Neonatal; Male; Pilot Projects; Risk Assessment; Sampling Studies; Survival Rate; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology